Handling dry ice requires caution and adherence to safety guidelines. Dry ice is extremely cold (-78.5°C or -109.3°F) and can cause frostbite or burns upon direct contact with skin. When handling dry ice, always wear insulated gloves and use tongs or protective tools to avoid skin contact. Store dry ice in a well-ventilated area, as it sublimates (converts from solid to gas) and releases carbon dioxide gas, which can displace oxygen in confined spaces. Do not store dry ice in airtight containers or sealed bags, as it can cause pressure buildup and rupture. Always follow proper storage, handling, and disposal procedures to ensure safety.